Plenary Lecture 7


Lawrence Ho

National University Health System, Singapore

The last century has seen the world being transformed through massive discovery and sharing of new knowledge. This century is likely to see how the new knowledge can be effectively utilised to create new values and sustain the transformative process. I believe one way to do this is to ensure that innovation and new knowledge addresses a key issue, and result in a big impact, the so-called closing the loop. I would like to share my personal journey with developing 3 technologies all the way from need (issue) to impact.

The first technology is the Master and Slave Transluminal Endoscopic Robot (MASTER), a ground breaking invention, which was successfully used to perform the world's first flexible robotic endoscopic submucosal dissection in human patients. Its significance lies in the potential of the platform in enabling 2-arm technique and telemedicine for future complex endoscopic procedures.

The second technology is the world’s one-of-a-kind In-Vivo Molecular Diagnostic System, which can be used to make realtime diagnosis of GI cancer simpler. Its significance lies in the ability of the technology to (i) obviate subjective structural recognition of images by operators, (ii) shorten learning curve, and (iii) reduce lag time in making the diagnosis.

The third technology is the weight loss capsule, which is an ingestible and expellable dose adjustable capsule able to help the patient to lose weight. It is still in the developmental phase.

In this talk, I will use these examples to illustrate how translational research can create value on top of the values already added by existing medical advancement. The talk will also explore some key success steps for translational research, innovation, and enterprise:- the 6 Is.


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